Try plugging in a Feliway diffuser before your cat comes into heat. This synthetic feline pheromone surrounds her with safe, familiar scents. [2] X Research source Pheromones are chemical messengers — a similar idea to the pheromones a female gives off to advertise she is in heat. But the ones in Feliway might have a calming, soothing effect on her. It doesn’t work immediately, but the pheromones build up the cat’s sense of well-being over a couple of weeks. As such, it’s best to plug the diffuser in early and leave it running constantly in the background, so she gets the benefit by the time she comes into heat.
Making sure she has a clean litter box at all times. Hopefully her house training will lead her to use the box instead of marking in the house. Deodorize immediately if she does mark. This will discourage her from returning to that spot to mark it again. Use an “enzymatic” cleaner to completely remove the urine odor. [3] X Research source The enzymes in these products break cat urine down better than any other cleaner. Allow the product to air dry for best results. A home-made alternative is to dilute some biological washing powder in water. Use this to clean the area, then rinse it with water. Clean again with a solution of bicarbonate of soda. Finish by rinsing one last time. Always test cleaning products on a small, hidden patch of fabric before treating a marked patch for odor.
She might seek out company far more than usual. She may demand that you rub her lower back. When you do, she might flirtatiously hold her tail to one side to better expose her genital area. She may ‘commando crawl’ across the floor by flattening her front half against the floor, then crawling with her rear end pushed up in the air. She is also likely to squirm and roll around enthusiastically. When combined with the loud crying, it might look like she’s in pain. Don’t worry — she’s just flirting. There’s nothing to be done about this behavior. It’s perfectly normal, and as long as no males are able to reach her, she’ll be fine.
Instead, leave large amounts of her regular cat food available for free-feeding. She can snack whenever she feels like it.
Again, Feliway takes a couple of weeks to build up in your cats’ systems, so plug in the diffuser before your female goes into heat.
Keep either the male(s) or female isolated in a separate room. Spruce the room up so the isolated cat doesn’t grow anxious. Put a litter box in there, along with a comfortable bed, food, and plenty of toys to keep them occupied.
Leaving doors or windows open, even with mosquito mesh acting as a barrier, can be dangerous. A determined male will claw through the mesh to reach your female, and she can get pregnant without even leaving the house. Block off any cat flaps in your doors.