One fast way to deal massive amounts of damage is to combine Pyro with Electro to result in Overloaded. You will also want a character that can regenerate your other characters’ health, such as Barbara. If you do not have a character that can restore HP, then you will need a lot of food, and you will need to pay attention very closely.

If you own the playable character Mona, you can use her alternate sprint to walk across water without swimming. You can also use a cryo character such as Kaeya or Chongyun to create an ice bridge.

The boss has the potential to deal lots of damage if you are unprepared. The arena has a huge square inscribed in the center.

You can use a Geo pillar as a shield, and the small rocks will degrade the pillar strength over time.

Also, combine the different elements together. One easy way to deal massive amounts of damage is to combine Pyro with Electro, resulting in Overloaded.

If you fail to destroy all three Geo pillars, then the Hypostasis will regenerate 15% of its maximum HP for each pillar remaining. Pillars that are destroyed once do not need to be destroyed again, so if you manage to destroy one Geo pillar, you will only need to destroy the two Geo pillars absorbed by the Hypostasis.